With only 1 injection, the results exceeded expectations: Can this become the most powerful Covid-19 vaccine?

Tram Ho

With just one injection, the results of the Johnson & Johnson vaccine exceeded expectations

Johnson & Johnson recently released the latest COVID -19 vaccine data.

Injectable dosage form: One dose of vaccine is sufficient to prevent Covid-19 infection, while the current Pfizer / BioNTech vaccine and the US approved Moderna vaccine must be given two shots separated from three to four weeks.

Duration of vaccination: One dose of vaccine can induce an immune response for at least 71 days.

Storage: Vaccines can be stored for 3 months at refrigerated temperatures, storage conditions do not require harsh freezing environments like Pfizer / BioNTech vaccines.

Side effects: The incidence of systemic side effects in volunteers over 65 years of age was lower than in young and middle-aged volunteers.

 Chỉ tiêm 1 mũi, kết quả vượt quá mong đợi: Đây có thể trở thành vắc xin Covid-19 mạnh nhất? - Ảnh 1.

Professor Carlos del Rio of Emory University, USA said, “If the Johnson & Johnson vaccine can actually achieve single-dose immunity, it will surely become the most popular vaccine on the market. Around the world”.

Johnson & Johnson then said: There could be an emergency license in the US as early as next month, and 60 million doses of the vaccine will be produced by April this year.

At the end of the day, Johnson & Johnson’s share price had risen to + 1.21%.

 Chỉ tiêm 1 mũi, kết quả vượt quá mong đợi: Đây có thể trở thành vắc xin Covid-19 mạnh nhất? - Ảnh 2.

The antibodies produced by the Johnson & Johnson vaccine:

The first dose is twice as much as the other vaccines, the second three times.

The results published this time by Johnson & Johnson belong to the Phase 1 / 2A clinical trial, with data from 805 volunteers.

For volunteers aged 18-55 years and 65 years and older, Johnson & Johnson researchers randomly assigned high-dose, low-dose and placebo vaccines. Some 18-55 year old volunteers also received a second shot.

The test results show:

In vaccinated volunteers, after 28 days, most people had detectable neutralizing antibodies.

On day 57, all people of different ages should be able to detect antibodies in the body.

In volunteers aged 18-55 years, antibodies should stabilize for at least 71 days.

Common vaccination side effects, such as fever, fatigue, headache, muscle aches and soreness at the injection site, are lower in seniors who received only one dose of the vaccine and in those who received a low dose than.

According to the latest research data in the New England Journal of Medicine, healthy adults 18 to 55 and 65 years of age and older were vaccinated at high or low doses, while others received a placebo. .

Johnson & Johnson’s single-dose Covid-19 vaccine is safe and has produced an effective immune response in young and elderly volunteers.

 Chỉ tiêm 1 mũi, kết quả vượt quá mong đợi: Đây có thể trở thành vắc xin Covid-19 mạnh nhất? - Ảnh 3.

An injection dose is equivalent to 2 doses, 2 doses injected, the antibody increased 3 times

Concurrently with the data publication, Scientist Paul Stoffels – President of Johnson & Johnson said: “Compared to other leading COVID-19 vaccines (Pfizer, Moderna and AstraZeneca), one dose of Johnson & Johnson vaccine. Johnson can produce more neutralizing antibodies, equivalent to two other doses of vaccine. If after 2 months of Johnson & Johnson vaccination, the number of antibodies to neutralize will triple. “.

“Data from this experiment suggest that a single vaccination can produce a persistent antibody in the body, which is expected to be highly effective in defeating COVID-19.”

 Chỉ tiêm 1 mũi, kết quả vượt quá mong đợi: Đây có thể trở thành vắc xin Covid-19 mạnh nhất? - Ảnh 4.

This data comes at a time when the US Centers for Disease Control and Prevention (CDC) expanded the scope of Covid-19 vaccinations to include people 65 years of age and older and people with medical conditions. before. The government is also changing the way vaccine doses are distributed.

If the Johnson & Johnson vaccine is approved by the US Food and Drug Administration, it will be the third vaccine approved for use in the US after Pfizer and Moderna.

Expected to be approved in February, the first Covid-19 adenovirus vectors vaccine.

It should be noted that there are currently two approved vaccines in the United States: the Pfizer / BioNTech vaccine and the Moderna vaccine.

Both of these are mRNA vaccines. The core is to use genetic instruction to teach cells to make specific proteins. One of the biggest advantages of mRNA technology is that it can be used to develop vaccines faster than traditional methods.

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Source : Genk