The Vietnam-made Covid-19 vaccine works with the new variant SARS-CoV-2
- Tram Ho
Military Medical Academy (Ministry of Defense) said that by this time, Vietnam has completed 120 injections for clinical trial of phase 1 Covid-19 Nano Covax vaccine for 60 volunteers. Twenty-two volunteers had just received the remaining 2 Covid-19 vaccines by the research team, including 2 volunteers from the 50 mcg dose group, and 20 volunteers from the 75 mcg dose group.
Through initial assessment, the research team showed that Covid-19 Nano Covax vaccine is safe, produces a good immune response, ensures safety, and is effective against SARS-CoV-2 virus, including variant strains. new form.
Most of the volunteers are in stable health after the injection. In rare cases, pain at the injection site, low fever but all after 1-2 days. After injection 2, the antibodies of the subjects were injected continue to increase. The team will continue to collect periodically for accurate assessment.
The first person in Vietnam conducted a trial vaccination of Nano Covax vaccine
Currently, the research team of the Military Medical Academy is processing data, sending documents to the Ministry of Health to determine the appropriate dose for phase 2, which is expected to start right after the Lunar New Year. It is expected that, right after the 2021 Lunar New Year, the Ethics Council in biomedical research (Ministry of Health) will meet and evaluate before approving the implementation of phase 2 test injection.
Previously, Associate Professor, Dr. Ho Anh Son, Deputy Director of the Military Medical Research Institute (Military Medical Academy), said phase 1 of the clinical trial aimed to focus on determining the safety of vaccines. To obtain and probe the optimal dose, to assess the immunogenicity response in three groups of 25 mcg, 50 mcg and 75 mcg doses.
Along with the trial of the Covid-19 Nano Covax vaccine phase 2, the Military Medical Academy began recruiting new phase volunteers with nearly 400 people registered to participate.
Covid-19 Nano Covax vaccine
In phase 2, the Military Medical Academy will test over 560 volunteers, lasting for 6 months with the participation of the Central Institute of Hygiene and Epidemiology and the Pasteur Institute of Ho Chi Minh City. Phase 3 will then begin as phase 2 goes halfway through the scale of injecting more than 10,000 volunteers, starting August 2021. This trial phase may extend in some countries with Covid-19 outbreaks in the community. If the experimental research works smoothly, it is expected that by the beginning of 2022, Vietnam will have a vaccine against Covid-19 produced by Vietnam.
Previously, the professional council of the Ministry of Health approved Covid-19 Nano Covax vaccine of Nanogen Biotechnology Joint Stock Company (Nanogen Company) as the first Covid-19 vaccine of Vietnam is included in the clinical trial. Nano Covax vaccine test injections were conducted on December 17, 2020 on 3 volunteers.
Covid-19 Nano Covax vaccine is based on recombinant technology, given 28 days apart. After 2 injections, volunteers were followed up to 6 months to evaluate the effectiveness of protection.
Covid-19 COVIVAC vaccine is the second Vietnamese vaccine to be tested in humans
In addition to Nanogen Company, the Institute of Vaccines and Medical Biologicals (IVAC) is recruiting volunteers for the clinical trial of COVIVAC vaccine. Vaccines studied by IVAC from May 2020 have carried out preclinical studies in India, the US and Vietnam, the results show safety and effectiveness in experiment, meeting all conditions. , the standard to be able to conduct research in humans.
Currently, there are 2 other units that are researching and manufacturing Covid-19 vaccines, including: Vaccine and Biologicals Company No. 1 (VABIOTECH) and Research Center for Vaccines and Medical Biologicals. (POLYVAC).
Source : Genk